Is Alzheimer’s hereditary? There are many disease that are heredity, so why not Alzheimer’s. There is presently research on a person’s blood type predicting the person’s risk for Alzheimer’s is high. Some cancers and diseases like diabetes, and some cardiac disease are hereditary, why not Alzheimer’s. Genetic research has turned up evidence of a link between Alzheimer’s disease and genes on four chromosomes. Dozens of studies around the world have confirmed that inheritance of one particular variant of a certain genes increases the lifetime risk of developing Alzheimer’s disease.
some diseases are caused by a genetic mutation, or change in one or more specific genes. If a person inherits from a parent a genetic mutation that causes a certain disease, then he or she will usually get the disease. Sickle cell anemia, cystic fibrosis, and early-onset familial Alzheimer’s disease are examples of inherited genetic disorders. In other diseases, a genetic variant may occur. This change in a gene can sometimes cause a disease directly. More often, it acts to increase or decrease a person’s risk of developing a disease or condition. Alzheimer’s disease is an irreversible, progressive brain disease.
Alzheimer’s disease strikes early and fairly often in certain families, often enough to be singled out as a separate form of the disease and given a label: early-onset familial Alzheimer’s disease, or FAD. Combing through the DNA of these families, researchers have found an abnormality in one gene on chromosome that is common to a few of the families. And they have linked a much larger proportion of early-onset families to recently identified and related genes on other chromosomes. Alzheimer’s genes are genes that make you more likely to develop Alzheimer’s disease. Genes control the function of every cell in your body. Some genes determine basic characteristics, such as the color of your eyes and hair. Other genes can make you more likely to develop certain diseases, including Alzheimer’s disease. Because you inherit one of the Alzheimer’s genes from your mother and another from your father, you have two copies the gene. Having at least one gene increases your risk of developing Alzheimer’s disease. If you have two genes, your risk is even higher.
Not everyone who has one or two genes develops Alzheimer’s disease. The disease occurs in many people who have no gene, suggesting that the gene affects risk but is not a cause. Other genetic and environmental factors likely are involved in the development of Alzheimer’s disease. The question many individuals ask should they be tested if there is a test for developing Alzheimer’s disease. Would people take the test to find out if they have the risk factors to develop Alzheimer’s? Scientists don’t yet fully understand what causes Alzheimer’s. However, the more they learn about this devastating disease, the more they realize that genes do play a very important role in its development. Researchers seek to learn more about the basic mechanisms of Alzheimer’s disease and, consequently, ways to treat and prevent the disease. Research conducted and funded by the National Institute on Aging (NIA) at the National Institutes of Health and others is advancing the field of Alzheimer’s disease genetics.
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